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U.S. examine suggests COVID-19 vaccines could also be ineffective in opposition to Omicron with out booster By Reuters


© Reuters. FILE PHOTO: Vials labelled “Moderna, Johnson & Johnson, Pfizer-BioNTech coronavirus illness (COVID-19) vaccine” are seen on this illustration image taken Could 2, 2021. REUTERS/Dado Ruvic

By Michael Erman

NEW YORK (Reuters) – All three U.S.-authorized COVID-19 vaccines seem like considerably much less protecting in opposition to the newly-detected Omicron variant of the coronavirus in laboratory testing, however a booster dose probably restores a lot of the safety, based on a examine launched on Tuesday.

The examine from researchers at Massachusetts Normal Hospital (MGH), Harvard and MIT that has not but been peer reviewed examined blood from individuals who obtained the Moderna (NASDAQ:), Johnson & Johnson (NYSE:) and Pfizer/BioNTech vaccines in opposition to a pseudovirus engineered to resemble the Omicron variant.

The researchers discovered “low to absent” antibody neutralization of the variant from the common regimens of all three vaccines – two pictures of the Moderna or Pfizer/BioNTech vaccines or one among J&J’s single-dose vaccine.

However the blood from current recipients of an extra booster dose exhibited potent neutralization of the variant, the examine discovered.

The scientists additionally recommended that Omicron is extra infectious than earlier variants of concern, together with about twice as transmissible because the presently dominant Delta variant, which can quickly be overtaken by Omicron.

The outcomes are consistent with different research not too long ago revealed. Researchers on the College of Oxford mentioned on Monday that they discovered the two-dose Pfizer (NYSE:) and AstraZeneca (NASDAQ:) COVID-19 vaccine regimens don’t induce sufficient neutralizing antibodies in opposition to the brand new variant.

BioNTech and Pfizer mentioned final week {that a} three-shot course of their COVID-19 vaccine was in a position to neutralize the brand new Omicron variant in a laboratory take a look at, however two doses resulted in considerably decrease neutralizing antibodies.

Moderna and J&J have but to launch any of their very own knowledge about how the vaccines carry out in opposition to the brand new variant. J&J declined to touch upon the brand new examine and Moderna didn’t reply to request for remark.

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